Brain age gap as a predictive biomarker that links aging, lifestyle, and neuropsychiatric health.
Abstract
The brain age gap (BAG) is a neuroimaging-derived marker of accelerated brain aging. However, its clinical application faces challenges due to model inaccuracies and unclear links to disease mechanisms. This study investigates the clinical relevance of BAG across neuropsychiatric disorders, cognitive decline, mortality, and lifestyle interventions.
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Research summary
The study investigates the clinical relevance of the brain age gap (BAG) in relation to neuropsychiatric disorders and lifestyle interventions. The paper is relevant as it explores a potential biomarker that could link aging processes with neuropsychiatric health, although it does not directly address root causes of aging.
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