Reproductive history and cardiometabolic disease: the role of endogenous estrogen exposure across the lifespan in postmenopausal women.

Yingze Zhu, Jialu Li, Wenjing Qin, Liang Wang, Qi Qi, Shaoru Li, Yue Cheng, Yuan Shen, Wenfang Yang, Zhonghai Zhu, Lingxia Zeng

Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China.Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China. · pubmed

Paper

Abstract

The association between cumulative endogenous estrogen exposure across the lifespan, especially considering reproductive events, and women's cardiometabolic health remain unclear. We aimed to examine the associations between lifetime endogenous estrogen exposure and the risks of diabetes, hypertension, and cardiovascular disease (CVD) among postmenopausal women.

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Research summary

The paper claims that cumulative endogenous estrogen exposure influences the risks of diabetes, hypertension, and cardiovascular disease in postmenopausal women. This research is relevant as it explores the role of hormonal factors in cardiometabolic health, which can contribute to understanding aging processes and longevity in women.

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