Neurophysiological assessment of bone mechanosensitivity using the bone myoregulation reflex.

Tuğba Aydın, Nilgün Yildiz, Aybike Ata, Eser Kalaoglu, Selim Sezikli, Mert Çetin, Nida Lale Köksal, Kadriye Öneş, Halime Kibar, Kemal Sitki Türker, Ilhan Karacan

Physical Therapy and Rehabilitation Department, Istanbul Physical Therapy Rehabilitation Training and Research Hospital, Adnan Kahveci Bulvarı No. 145, 34186, Bahçelievler/Istanbul, Turkey. [email protected] Therapy and Rehabilitation Department, Istanbul Physical Therapy Rehabilitation Training and Research Hospital, Adnan Kahveci Bulvarı No. 145, 34186, Bahçelievler/Istanbul, Turkey. [email protected]. · pubmed

Paper

Abstract

Mechanical loading is essential for bone growth, development, and skeletal integrity, and these effects are mediated primarily by osteocytes, the principal mechanosensory cells of bone. Aging and osteoporosis can impair osteocytes and the lacunocanalicular system, leading to bone loss, reduced biomechanical quality, and increased fragility. The bone myoregulation reflex may offer a noninvasive means of evaluating bone mechanosensitivity and quality.

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Research summary

The paper claims that the bone myoregulation reflex can be used to assess bone mechanosensitivity and quality. This research is relevant as it addresses the mechanosensitivity of bone, which is crucial for understanding and potentially mitigating age-related bone loss and fragility.

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