The Bidirectional Casual Relationships between Chronic Inflammation and Intrinsic Capacity Decline: Insights from Mendelian Randomization Analysis.
Abstract
Intrinsic capacity, encompassing locomotion, vitality, cognition, psychology, and sensory function, is a critical determinant of healthy aging, yet its association with inflammatory markers remains poorly understood due to confounding factors in observational studies.
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Research summary
The paper claims that there are bidirectional causal relationships between chronic inflammation and intrinsic capacity decline. This research is relevant as it explores the underlying mechanisms of aging and how chronic inflammation may contribute to the decline in intrinsic capacity, which is essential for healthy aging.
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