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RESEARCH PAPER / 2025-10-16

Sex-specific dynamic changes of serum short-chain fatty acids in rhesus monkeys during aging.

Xiaopeng Chen, Songyuan Ye, Juncai Pu, Siwen Gui, Dongfang Wang, Xiaogang Zhong, Weiyi Chen, Yue Chen, Xiang Chen, Yanyi Jiang, Renjie Qiao, Yiyun Liu, Peng Xie

Department of Neurology, NHC Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. · pubmed

Abstract

The potential association between short-chain fatty acids (SCFAs) and aging has gained increasing research attention. Although most studies have focused on fecal SCFAs, limited attention has been directed toward SCFAs in peripheral blood. Furthermore, this relationship remains insufficiently explored in non-human primate models.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that there are sex-specific dynamic changes in serum short-chain fatty acids during aging in rhesus monkeys. This research is relevant as it explores the relationship between metabolic changes and aging, potentially contributing to our understanding of the biological mechanisms underlying aging processes.

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