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RESEARCH PAPER / 2025-10-13

Age and physical activity modulate miRNAs contained in human follicular fluid extracellular vesicles.

Maria Soares, Carmen Almiñana, Ana Filipa Ferreira, Alexandra Carvalho, Francisca Costa, Rita Silva, Raquel Brito, Conceição Dias, Mariana Moura-Ramos, Teresa Almeida-Santos, Stefan Bauersachs, João Ramalho-Santos, Ana Paula Sousa

University of Coimbra, Institute for Interdisciplinary Research, Doctoral Program in Experimental Biology and Biomedicine (PDBEB), Coimbra, Portugal.University of Coimbra, Institute for Interdisciplinary Research, Doctoral Program in Experimental Biology and Biomedicine (PDBEB), Coimbra, Portugal. · pubmed

Abstract

Aging and lifestyle interventions alter extracellular vesicle cargo in fluids. In human follicular fluid, the miRNA content of extracellular vesicles is altered with aging and physical activity.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that aging and physical activity influence the miRNA content of extracellular vesicles in human follicular fluid. This research is relevant as it explores the molecular mechanisms by which aging and lifestyle factors may affect biological processes, potentially contributing to our understanding of aging and longevity.

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