Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.

Zimo Pan, Jing Zeng, Zeyu Chen, Shimin Chen, Junhan Yang, Huaihao Li, Shengshu Wang, Jianhua Wang, Nan Li, Yanping Gong, Miao Liu, Chunlin Li

Department of Endocrinology, the Second Medical Center & National Clinical Research Center for Geriatric Disease, Chinese PLA General Hospital, Beijing 100853, China. · pubmed

Paper

Abstract

The possible joint association of vitamin D and obesity in regard to the clinical biomarker-based biological aging process has not been well studied. We aimed to investigate the independent and combined associations of serum 25-hydroxyvitamin D [25(OH)D] concentrations and body mass index (BMI) with phenotypic age (PhenoAge) and Klemera-Doubal method Biological Age (KDM-BA) acceleration.

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Research summary

The paper investigates the combined effects of serum 25-hydroxyvitamin D levels and body mass index on biological aging markers. This study is relevant as it explores potential factors that may influence the biological aging process, which is central to longevity research.

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