Differential contributions of cardiovascular health-related lifestyle factors to epigenetic ageing: implications for healthy longevity.
Abstract
Lifestyle and cardiovascular health (CVH) are key determinants of the biological ageing process, which is closely linked to healthy ageing and longevity. Multiple CVH factors may interact and exert combined effects on the biological ageing process; however, studies exploring their collective association, particularly in Asian cohorts, remain limited. In this cross-sectional study, we investigated the relative contributions of CVH-related behaviours (diet, sleep, avoidance of nicotine, and physical activity) and clinical indicators (BMI, blood lipids, blood glucose, and blood pressure) to epigenetic age acceleration (EAA), as well as their collective associations.
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Research summary
The paper claims that various cardiovascular health-related lifestyle factors collectively influence epigenetic age acceleration. This research is relevant as it explores the interplay between lifestyle choices and biological aging, contributing to our understanding of factors that may promote healthy longevity.
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