The role of phenylalanine and tyrosine in longevity: a cohort and Mendelian randomization study.

Jie V Zhao, Yitang Sun, Junmeng Zhang, Kaixiong Ye

School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. · pubmed

Abstract

Protein restriction increases lifespan, however, the specific amino acids affecting lifespan are unclear. Tyrosine and its precursor, phenylalanine, may influence lifespan through their response to low-protein diet, with possible sex disparity.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the role of phenylalanine and tyrosine in influencing lifespan through dietary protein restriction. This study is relevant as it explores specific amino acids that may affect longevity, contributing to the understanding of dietary impacts on aging.

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