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RESEARCH PAPER / 2025-10-03

Lactate promotes longevity through redox-driven lipid remodeling in

Arnaud Tauffenberger, Payton J Netherland, Hubert Fiumelli, Joshua D Meisel, Frank C Schroeder, Pierre Magistretti

Not availableNot available · pubmed

Abstract

Lactate has emerged as a key metabolite involved in multiple physiological processes, including memory formation, immune response regulation, and muscle biogenesis. However, its role in aging and cellular protection remains unclear. Here, we show that lactate promotes longevity in

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Research summary

Lactate promotes longevity through redox-driven lipid remodeling. The paper investigates lactate's role in promoting longevity, addressing mechanisms that could influence aging processes rather than merely treating age-related symptoms.

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