Impacts of sarcopenia and resistance exercise training on mitochondrial quality control proteins.
Abstract
The progression of sarcopenia with aging may be related to mitochondrial dysfunction due in part to altered mitochondrial dynamics (fusion, fission, mitophagy, and biogenesis). Previous work has identified altered expression of proteins associated with these processes in with aging, but whether further changes occur in sarcopenia remains unclear.
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Research summary
The paper claims that resistance exercise training may influence mitochondrial quality control proteins in the context of sarcopenia. This research is relevant as it explores the underlying mechanisms of aging-related muscle loss and potential interventions that could mitigate these effects, addressing a root cause of aging.
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