Intermittent fasting attenuates glial hyperactivation and photoreceptor degeneration in a NaIO

Jingzhen Li, Beibei Wang, Pinjie Liu, Xuecheng Qiu, Qiyun Bian, Congxin Shen, Yanyan Li, Mengwen Shao, Meng Li

Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Xuzhou, Jiangsu, 221000, China. · pubmed

Paper

Abstract

Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss, with limited treatments available. Recent studies suggest intermittent fasting (IF) may offer neuroprotective benefits for aging and age-related disorders, but its efficacy in AMD has not yet been established. Here, using a sodium iodate (NaIO

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Research summary

Intermittent fasting may provide neuroprotective benefits against age-related macular degeneration. The study addresses a potential intervention (intermittent fasting) that could impact the underlying mechanisms of aging and age-related diseases, specifically targeting neuroprotection in the context of AMD.

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