Muscle-Specific Strength Better Predicts Physical Performance Decline Than Conventional Metrics: The I-Lan Longitudinal Aging Study.
Abstract
Muscle-specific strength (MSS), defined as grip strength normalized to arm muscle mass, may better reflect muscle efficiency than grip strength. Despite its potential utility in diagnosing sarcopenia, longitudinal studies evaluating MSS as a predictor of sarcopenia-related outcomes remain limited. This study investigated the associations of MSS with physical performance deterioration and biomarker profiles in community-dwelling older adults, compared it with conventional measures, determined whether MSS-defined sarcopenia offers superior predictive utility versus traditional diagnostic criteria and examined associations with key cardiometabolic and inflammatory biomarkers.
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Research summary
Muscle-specific strength is a better predictor of physical performance decline in older adults than conventional metrics. This study is relevant as it explores a potential biomarker for sarcopenia, which is a significant age-related condition affecting longevity and quality of life in older populations.
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