Prognostic value of blood epigenetic biomarkers of aging in persons with well controlled HIV infection.

Patricia Martínez Martín, Andrés Esteban-Cantos, Francisco Jurado, Rocío Montejano, Lucía Gutiérrez-García, Alejandro de Gea Grela, Juan Carlos González, Cristina Marcelo, Alejandro Díez-Vidal, María Del Mar Arcos-Rueda, Rosa De Miguel Buckley, Jose I Bernardino, María Jiménez-González, María de Lagarde, José Sanz Moreno, Pablo Ryan, Vicente Estrada Pérez, Leire Pérez-Latorre, Juan Emilio Losa-García, Berta Rodés, José R Arribas

Department of Internal Medicine, Infectious Diseases Unit, La Paz University Hospital, Madrid,Spain. · pubmed

Paper

Abstract

Epigenetic age acceleration (EAA) predicts morbidity and mortality in the general population, but its prognostic utility in people with HIV (PWH) on suppressive antiretroviral therapy remains unclear.

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Research summary

The paper investigates the prognostic value of blood epigenetic biomarkers of aging in individuals with well-controlled HIV infection. This research is relevant as it explores the relationship between epigenetic age acceleration and health outcomes in a specific population, contributing to the understanding of aging processes in the context of chronic diseases.

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