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RESEARCH PAPER / 2025-09-27

Serum Vitamin C concentrations are inversely related to biological aging: a population-based cross-sectional study.

Ying Zhang, Fang Gong, Ai-Hua Zhang, Guan-Wu Wang, Yun Liu, Teng Li

Department of Laboratory Medicine, Obstetrics and Gynecology Hospital of Fudan University, No.419 Fangxie Road, Shanghai, 200011, China. · pubmed

Abstract

Vitamin C (Vit C), which has antioxidant properties, may reduce oxidative stress and delay aging. However, the relationship between Vit C and biological aging is poorly established. Therefore, we aimed to investigate the association between serum Vit C (S-vit C) concentrations and phenotypic age acceleration (PhenoAgeAccel), an indicator of biological aging.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Higher serum Vitamin C concentrations are associated with reduced biological aging as measured by PhenoAgeAccel. This study investigates a potential link between an antioxidant and biological aging, addressing a root cause of aging rather than merely treating symptoms.

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