The association between dietary total antioxidant capacity and gene expression of Klotho in Iranians.

Zahra Rahimi, Monirsadat Mirhoseini, Ghazaleh Eslamian, Arman Ghorbani, Hamid Zand, Safoura Vasheghani Farahani

Department of Cellular and Molecular Nutrition, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. · pubmed

Paper

Abstract

Oxidative stress plays a pivotal role in cellular aging, and dietary antioxidants may modulate this process through regulation of the aging-related Klotho gene. This cross-sectional study investigated the association between dietary total antioxidant capacity (DTAC) and Klotho gene expression in 50 healthy Iranian adults (aged 18-40 years).

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Research summary

The paper claims that higher dietary total antioxidant capacity is associated with increased expression of the Klotho gene in healthy adults. This study is relevant as it explores the relationship between dietary antioxidants and a gene implicated in aging, potentially contributing to our understanding of mechanisms that influence longevity.

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