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RESEARCH PAPER / 2025-09-26

Unveiling the genetic biomarkers for ageing: evidence from a large sample genome-wide association study and in vivo validation.

Zhikang Cai, Yue Yang, Peng Qu, Sensong Fu, Xu Li

Department of Emergency Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.Department of Emergency Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China. · pubmed

Abstract

Ageing, marked by cumulative molecular damage, now leaves most adults spending nearly a decade in poor health. To date, no therapies directly target the ageing process. We performed a large-scale genome-wide association study to identify potential drug targets for extending health span.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper identifies genetic biomarkers associated with aging that could serve as potential drug targets for extending health span. This research is relevant as it aims to address the underlying mechanisms of aging rather than merely treating age-related diseases.

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