RESEARCH PAPER / 2025-09-26
Periodontitis-induced Systemic Multi-organ Aging Mediated by the NF-κB Signalling Pathway.
Abstract
To investigate the causal role of periodontitis in inducing distal-organ aging and elucidate the mechanism between periodontitis and multi-organ aging by assessing the role of NF-κB signalling in mediating cellular senescence.
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Research summary
Periodontitis induces systemic multi-organ aging through the NF-κB signalling pathway. This research is relevant as it explores a potential root cause of aging by linking an inflammatory condition to multi-organ aging, which could inform strategies for longevity and age-related disease prevention.
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