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RESEARCH PAPER / 2025-09-21

Glycemic status, early-onset and late-onset dementia, dementia-free lifespan, and brain structure: A population-based cohort study.

Chenglong Li, Daijun He, Chao Yang, Luxia Zhang, Rodica Pop-Busui

National Institute of Health Data Science at Peking University, Beijing 100191, China; Institute of Medical Technology, Health Science Center of Peking University, Beijing 100191, China. · pubmed

Abstract

To evaluate associations of glycemic status with incident early-onset dementia (EOD) and late-onset dementia (LOD), dementia-free life expectancy, brain MRI structure measures, as well as the mediation pathway of depressive episode.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the associations between glycemic status and the incidence of early-onset and late-onset dementia, as well as dementia-free life expectancy. This research is relevant as it explores potential links between metabolic health and cognitive aging, which could inform strategies for promoting longevity and addressing age-related diseases.

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