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RESEARCH PAPER / 2025-09-18

Eight-week Flexi-bar vibration exercise enhances cognitive function via altering the circulating levels of BDNF, TNF-α, and microRNAs in middle-aged and elderly women.

Jiarui Wu, Dongdong Gao, Lu Leng, Younian Mai, Chen Huang, Min Hu, Junhao Huang

Guangdong Provincial Key Laboratory of Physical Activity and Health Promotion, Guangzhou Sport University, Guangzhou, Guangdong, China.Guangdong Provincial Key Laboratory of Physical Activity and Health Promotion, Guangzhou Sport University, Guangzhou, Guangdong, China. · pubmed

Abstract

Appropriate physical exercise could prevent, delay, or reverse cognitive decline in aging people, which could improve their quality of life. However, the underlying mechanisms are still elusive. The present study aimed to explore the effects of 8-week Flexi-bar vibration exercise (FE) on the cognitive function in middle-aged and elderly women and uncover the underlying mechanisms.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that eight weeks of Flexi-bar vibration exercise enhances cognitive function in middle-aged and elderly women by altering levels of BDNF, TNF-α, and microRNAs. This study is relevant as it explores the potential of physical exercise to improve cognitive function, which is a significant aspect of aging and longevity research.

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