Circadian Rhythms in Aging and Age-Related Neurogenerative Disease.

Kirsi-Marja Zitting, Robin K Yuan

Department of Medicine and Neurology, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA. · pubmed

Paper

Abstract

Age-related changes in the circadian timing system may play a role in the development of disorders in older age. We review key aspects of the human circadian system that change with aging, discuss recent evidence of how changes in sleep and circadian rhythms manifest in neurodegenerative diseases, and summarize research on new therapies.

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Research summary

Age-related changes in the circadian timing system may contribute to the development of neurodegenerative diseases. The paper is relevant as it explores how circadian rhythms, which are fundamental to biological processes, may influence aging and age-related diseases, potentially addressing underlying mechanisms rather than just symptoms.

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