Zhenqi Buxu oral liquid ameliorates inflammaging and aging associated dysfunction via downregulation of TNF-ɑ-mediated inflammatory pathways in mice.

Xinqing Jiang, Weidong Ye, Zhengkai Wang, Keying Zhu, Jun Ping, Liujun Xu, Beier Jiang, Shengmei Zhu, Maoxiang Qian, Lifeng Xu, Feng Zhang, Sijia Chen

Jinhua Graduate Joint Training Base, Zhejiang Chinese Medical University, Quzhou People's Hospital, Quzhou, 324000, China.Jinhua Graduate Joint Training Base, Zhejiang Chinese Medical University, Quzhou People's Hospital, Quzhou, 324000, China. · pubmed

Paper

Abstract

Aging is associated with a persistent, low-grade inflammatory state termed "inflammaging", driven by the accumulation of senescent cells and their senescence-associated secretory phenotype (SASP). Zhenqi Buxu Oral Liquid (ZQBX) is a widely used traditional Chinese medicine formula known to treat human weakness and have potential anti-aging effects.

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Research summary

Zhenqi Buxu Oral Liquid ameliorates inflammaging and aging-associated dysfunction by downregulating TNF-ɑ-mediated inflammatory pathways in mice. The paper addresses the underlying inflammatory processes associated with aging, which is a key aspect of longevity research.

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