Bacterial porphyrins in healthy skin: Microbiota components impact melanogenesis and age-related processes leading to Porphyr'ageing.

Marie Meunier, Morgane De Tollenaere, Cyrille Jarrin, Emilie Chapuis, Marine Bracq, Laura Lapierre, Catherine Zanchetta, Jean Tiguemounine, Amandine Scandolera, Romain Reynaud

Givaudan Active Beauty, Research and Development, Givaudan France SAS, Argenteuil, France.Givaudan Active Beauty, Research and Development, Givaudan France SAS, Argenteuil, France. · pubmed

Paper

Abstract

Porphyrins are ubiquitous metabolites and are constitutive of the bacterial metabolome of healthy skin. Their consideration has until now been limited to their pro-inflammatory activity in acne vulgaris. The present work suggests a new role for these molecules in the onset of skin ageing.

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Research summary

The paper claims that bacterial porphyrins in healthy skin influence melanogenesis and age-related processes. This research is relevant as it explores a potential new role of bacterial metabolites in skin aging, which could contribute to understanding the biological mechanisms of aging.

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