Study Protocol of the 10-year longitudinal Amersfoort Cohort Study on Functional decline, Healthy aging, and Frailty (AMCOHF) in a community-dwelling older population.
Abstract
Frailty, characterized by a reduction in intrinsic capacity across multiple physiological systems, is a key concern in healthy aging. Insight in the trajectory of an individual's functional ability and intrinsic reserve capacity in a relatively younger population of older adults is lacking. This study aims to investigate the early stages of frailty by tracking trajectories of physical indicators of intrinsic capacity before frailty becomes clinically evident.
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Research summary
The study aims to track the early stages of frailty in older adults to understand functional decline and intrinsic capacity. This research is relevant as it addresses the underlying mechanisms of frailty, which is a significant aspect of healthy aging and longevity.
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