Ergothioneine as a promising natural antioxidant: bioactivities, therapeutic potential, and industrial applications.

Ziteng Lei, Zhong Wang, Haijing Zhang, Yan Jia, Di Zhang, Ruoyu Shi, Chengtao Wang, Wei Chen

Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering and Technology Research Center of Food Additives, School of Food and Health, Beijing Technology and Business University, Beijing 100048, PR China. [email protected] Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering and Technology Research Center of Food Additives, School of Food and Health, Beijing Technology and Business University, Beijing 100048, PR China. [email protected]. · pubmed

Paper

Abstract

Ergothioneine (EGT) is a naturally occurring thiol-containing amino acid derivative synthesized by certain fungi and bacteria, with humans acquiring it exclusively through dietary intake. It has gained increasing attention due to its exceptional antioxidant, cytoprotective, and metal-chelating properties. EGT shows high stability under physiological conditions and can accumulate in specific tissues

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Research summary

The paper claims that ergothioneine possesses exceptional antioxidant and cytoprotective properties that may contribute to healthspan and longevity. The focus on a natural compound with potential protective effects against oxidative stress aligns with longevity research.

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