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RESEARCH PAPER / 2025-09-05

Artificial intelligence oculomics for systemic health and longevity medicine: 2025 and beyond.

Jie Yao, Ashley Shuen Ying Hong, Kanae Fukutsu, Daniel Shu Wei Ting

Singapore National Eye Center, Singapore Eye Research Institute.Singapore National Eye Center, Singapore Eye Research Institute. · pubmed

Abstract

With the rise of 'oculomics' and the application of advanced artificial intelligence techniques in healthy ageing, retinal imaging, the only way we can directly visualize the microvascular circulation, is expanding beyond ophthalmology into broader systemic health monitoring. The purpose of this review is to summarize recent advances in this rapidly evolving field and assess the opportunities, challenges, and future directions of the use of oculomics in translating into real-world clinical use.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper discusses the potential of oculomics and AI in monitoring systemic health through retinal imaging. This is relevant as it explores innovative approaches to understanding and potentially addressing the underlying mechanisms of aging and systemic health, rather than merely treating age-related diseases.

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