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RESEARCH PAPER / 2025-09-02

Serum Galectin-9 and Decorin in relation to brain aging and the green-Mediterranean diet: A secondary analysis of the DIRECT PLUS randomized trial.

Dafna Pachter, Anat Yaskolka Meir, Alon Kaplan, Gal Tsaban, Hila Zelicha, Ehud Rinott, Gidon Levakov, Ofek Finkelstein, Ilan Shelef, Moti Salti, Frauke Beyer, Veronica Witte, Nora Klöting, Berend Isermann, Uta Ceglarek, Tammy Riklin Raviv, Matthias Blüher, Michael Stumvoll, Dong D Wang, Frank B Hu, Meir J Stampfer, Galia Avidan, Iris Shai

The Health & Nutrition Innovative International Research Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, David Ben-Gurion Blvd. 1, Beer-Sheva, 8410501, Israel.The Health & Nutrition Innovative International Research Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, David Ben-Gurion Blvd. 1, Beer-Sheva, 8410501, Israel. · pubmed

Abstract

We explored whether changes in serum proteomic profiles differed between participants with distinct brain aging trajectories, and whether these changes were influenced by dietary intervention.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the relationship between serum proteomic profiles and brain aging in the context of dietary intervention. This research is relevant as it explores potential biological markers and dietary influences on brain aging, which could contribute to understanding the mechanisms of aging and longevity.

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