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RESEARCH PAPER / 2025-09-01
REV-ERBα regulates brain NAD
Jiyeon Lee, Ryeonghwa Kang, Sohui Park, Ibrahim O Saliu, Minsoo Son, Jaymie R Voorhees, Julie M Dimitry, Elsa I Quillin, Lauren N Woodie, Brian V Lananna, Li Gan, Young-Ah Goo, Guoyan Zhao, Mitchell A Lazar, Thomas P Burris, Erik S Musiek
Department of Neurology and Center On Biological Rhythms And Sleep, Washington University in St. Louis School of Medicine, St. Louis, MO, USA. [email protected] of Neurology and Center On Biological Rhythms And Sleep, Washington University in St. Louis School of Medicine, St. Louis, MO, USA. [email protected]. · pubmed
Abstract
Nicotinamide adenine dinucleotide (NAD
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Research summary
REV-ERBα regulates brain NAD levels. The regulation of NAD, a crucial coenzyme involved in cellular metabolism and energy production, is relevant to understanding mechanisms of aging and potential interventions for lifespan extension.
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