Sea cucumber polypeptide ameliorates aging properties via the brain-gut axis in naturally aging mice.

Chao Feng, Yiwen Shou, Shulin Wu, Han Mo, Xin Mao, Huisha Huang, Qinpei Lu, Li Xia, Lu Lu, Zhiheng Su, Hongwei Guo, Zhaoquan Huang

Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China. · pubmed

Paper

Abstract

Sea cucumber has been recognized as a traditional nutraceutical in Chinese medicine for millennia, with its derived polypeptide (SCP) demonstrating diverse bioactive properties. Nevertheless, the molecular mechanisms underlying SCP's potential geroprotective effects remain insufficiently characterized.

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Research summary

The paper claims that sea cucumber polypeptide can ameliorate aging properties via the brain-gut axis in naturally aging mice. This research explores a potential intervention targeting the biological mechanisms of aging, which aligns with longevity research.

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