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RESEARCH PAPER / 2025-08-30

HIV infection is associated with accelerated epigenetic ageing: A systematic review.

Mateusz Bożejko, Brygida Knysz, Anna Czernicka, Ignacy Tarski, Aleksandra Szymczak, Małgorzata Małodobra-Mazur

Department of Infectious Diseases, Liver Disease and Acquired Immune Deficiencies, Wroclaw Medical University, Koszarowa 5, Wrocław 51-149, Poland. Electronic address: [email protected]. · pubmed

Abstract

We conducted a systematic review of studies comparing the intensity of epigenetic ageing in people living with human immunodeficiency virus (HIV) and uninfected individuals. We included studies that quantitatively examined the intensity of age-related epigenetic changes in both groups.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

HIV infection is associated with accelerated epigenetic ageing in individuals compared to uninfected individuals. This paper is relevant as it explores the relationship between a viral infection and epigenetic changes that may contribute to the understanding of aging processes.

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