Effects of Spermidine-Rich Rice Germ Extract Supplement on Biomarkers of Healthy Aging and Autophagy-Proof-of-Concept Pilot Study.

Gene Bruno, Michael La Monica, Tim N Ziegenfuss

Professor Emeritus of Nutraceutical Science of Huntington University of Health Sciences, Chief Scientific Officer of Nutraland, USA.Professor Emeritus of Nutraceutical Science of Huntington University of Health Sciences, Chief Scientific Officer of Nutraland, USA. · pubmed

Paper

Abstract

Although epidemiological and preclinical research suggests that the polyamine spermidine improves the efficiency of autophagy, human clinical research demonstrating a specific dose of any source of spermidine capable of increasing biomarkers of autophagy is lacking.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that a specific dose of spermidine-rich rice germ extract can increase biomarkers of autophagy in humans. This research is relevant as it explores a potential intervention that may enhance autophagy, a process linked to healthy aging and longevity.

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