Induced somatic mutation accumulation during skeletal muscle regeneration reduces muscle strength.

Peter Vrtačnik, Lara G Merino, Santhilal Subhash, Hafdís T Helgadóttir, Matthieu Bardin, Fabiana Stefani, Depin Wang, Ping Chen, Irene Franco, Gwladys Revêchon, Maria Eriksson

Department of Medicine, Huddinge, Karolinska Institutet, Huddinge, Sweden. · pubmed

Paper

Abstract

Aging is associated with a progressive decline in tissue function and regenerative capacity, partly due to genomic instability, one of the hallmarks of aging

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Induced somatic mutation accumulation during skeletal muscle regeneration reduces muscle strength. The paper addresses genomic instability in the context of muscle regeneration, which is a fundamental aspect of aging and its impact on tissue function.

Author of this paper? Send a correction.