Modulating biological aging with food-derived signals: a systems and precision nutrition perspective.

Carsten Carlberg, Andreas Blüthner, Irini Schoeman-Giziakis, Annemarie Oosting, Luca Cocolin

Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland. [email protected] of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland. [email protected]. · pubmed

Paper

Abstract

Lifespan extension has not prevented age-related decline. We propose that diet acts as a molecular modulator of aging, influencing inflammation, the microbiome, and systemic resilience. Biological age markers and AI-powered multi-omics reveal actionable dietary targets, including food-derived signals and Nutrition Dark Matter. We highlight precision nutrition and the EIT Food Healthy Aging Think & Do Tank as pathways to align science, policy, and practice for healthy aging.

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Research summary

Diet modulates biological aging through food-derived signals and precision nutrition strategies. The paper addresses the root causes of aging by proposing dietary interventions that could influence biological age and systemic resilience, making it relevant to longevity research.

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