Functionalized transdermal collagen mimetic peptides for efficient repair of subacute aged skin.

Jingting Zhang, Guangyu Liu, Yi Yang, Yi Xie, Linyan Yao, Jianxi Xiao

State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu, 730000, P. R. China. [email protected] Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu, 730000, P. R. China. [email protected]. · pubmed

Paper

Abstract

Skin aging compromises both aesthetic appearance and barrier function, presenting significant challenges for dermal regeneration. Collagen represents a crucial target for anti-aging interventions; however, they suffer from the risk of virus transmission, large molecular weight and difficulty in transdermal transmission. Herein, we designed a series of transdermal collagen mimetic peptides (TSTPs) and a functionalized transdermal collagen mimetic peptide for efficient repair of subacute aged skin. TSTP-2, with the sequence (GPO)

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Research summary

The paper claims that functionalized transdermal collagen mimetic peptides can efficiently repair subacute aged skin. This research addresses a specific aspect of skin aging, which is a fundamental component of the aging process, making it relevant to longevity research.

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