Biological age acceleration predicts osteoporosis and reduced longevity in a large prospective cohort.

Rui Zhang, Wanyang Zhong, Yuelan Gao, Xingxiang Duan, Qingsong Ye

Center of Regenerative Medicine, Renmin Hospital of Wuhan University, Wuhan 430060, China. · pubmed

Abstract

Osteoporosis is a major age-related musculoskeletal condition, yet chronological age does not fully capture individual risk. Biological age acceleration (BAA), as a biomarker of systemic aging, may offer greater predictive value for osteoporosis and lifespan loss.

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Research summary

Biological age acceleration is a predictive biomarker for osteoporosis and reduced longevity. The study addresses biological age as a factor in aging-related diseases, which is pertinent to understanding and potentially mitigating the root causes of aging.

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