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RESEARCH PAPER / 2025-08-16

Life course socioeconomic disadvantage and persistent infection burden: Links to cellular immunosenescence in U.S. young adults.

Jennifer Momkus, Kathleen Mullan Harris, Y Claire Yang, Chantel L Martin, Jessie K Edwards, Allison E Aiello

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina Chapel Hill, United States; Carolina Population Center, University of North Carolina Chapel Hill, United States. Electronic address: [email protected] of Epidemiology, Gillings School of Global Public Health, University of North Carolina Chapel Hill, United States; Carolina Population Center, University of North Carolina Chapel Hill, United States. Electronic address: [email protected]. · pubmed

Abstract

Socioeconomic status (SES) disadvantage shapes exposure to persistent infections and immune aging, but its life-course effects remain understudied. Early adulthood is a crucial period, as immune aging may begin before clinical signs appear.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that life course socioeconomic disadvantage is linked to persistent infection burden and cellular immunosenescence in young adults. This research is relevant as it explores the connections between socioeconomic factors and immune aging, which are critical to understanding the root causes of aging and potential interventions for longevity.

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