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RESEARCH PAPER / 2025-08-13

Life Course Adversity, Premature Mortality, and Life Expectancy: Role of Life's Essential 8.

Jinqi Wang, Yixing Tian, Xiaoyu Zhao, Chen Sheng, Haibin Li, Xia Li, Haiping Zhang, Lixin Tao, Zhiyuan Wu, Xiuhua Guo, Ding Ding

Beijing Key Laboratory of Environment and Aging, Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China.Beijing Key Laboratory of Environment and Aging, Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China. · pubmed

Abstract

Life course adversity has been linked to various health outcomes, but the interrelationship between adversity, Life's Essential 8 (LE8), and premature mortality remains unclear. We aimed to examine the associations of childhood and adulthood adversity with premature mortality and life expectancy, and whether LE8 modifies these associations.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper examines the associations between life course adversity and premature mortality, with a focus on how Life's Essential 8 may influence these relationships. This research is relevant as it explores factors that could potentially impact longevity and life expectancy, addressing root causes of health disparities related to aging.

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