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RESEARCH PAPER / 2025-08-13

Aging as a key determinant of glymphatic system function in older adults.

Feiyue Yin, Bang Zeng, Lisha Nie, Shuang Ding, Dan Luo, Peng Zeng, Binglan Li, Zhuowei Shi, Yongmei Li, Tianyou Luo

Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China. · pubmed

Abstract

The glymphatic system is a crucial pathway for the clearance of metabolic waste in the central nervous system. However, the risk factors of glymphatic system such as age, gender, metabolic factors, cardiovascular disease, and lifestyle are not fully investigated. We examined the association between risk factors and glymphatic system to identify the key factors that influence glymphatic system in older adults.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper examines the association between various risk factors and the glymphatic system in older adults. This research is relevant as it explores a potential mechanism related to aging and metabolic waste clearance, which could inform strategies for addressing age-related cognitive decline.

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