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RESEARCH PAPER / 2025-08-12

Physical Fitness, Biological Aging, and Healthy Longevity.

Ziyuan Chen, Paul James Collings, Mengyao Wang, Qiaoxin Shi, Shan Luo, Shiu Lun Au Yeung, Soren Brage, Tomas Gonzales, Youngwon Kim

School of Public Health, The University of Hong Kong Li Ka Shing Faculty of Medicine, Pokfulam, Hong Kong.School of Public Health, The University of Hong Kong Li Ka Shing Faculty of Medicine, Pokfulam, Hong Kong. · pubmed

Abstract

Physical fitness, particularly cardiorespiratory fitness (CRF) and muscle strength, is associated with reduced disease risk. However, its combined association with biological aging in promoting healthy longevity remains unanswered. We investigated whether cardiorespiratory fitness (CRF) and muscle strength could modify the prospective associations between accelerated biological aging and premature termination of healthy longevity.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that cardiorespiratory fitness and muscle strength can modify the relationship between biological aging and healthy longevity. This research is relevant as it explores the potential of physical fitness to influence biological aging processes, which is central to understanding and promoting healthy longevity.

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