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RESEARCH PAPER / 2025-08-09

Prenatal exposure to genocide accelerates epigenetic aging in third- and fourth-generation clocks among young adults in Rwanda.

Glorieuse Uwizeye, Luisa M Rivera, Hannah G Stolrow, Brock C Christensen, Julienne N Rutherford, Zaneta M Thayer

Arthur Labatt Family School of Nursing, Western University, London, Canada. [email protected] Labatt Family School of Nursing, Western University, London, Canada. [email protected]. · pubmed

Abstract

Prenatal exposure genocide-related to trauma has been previously associated with increased morbidity. Whether the prenatal exposure to genocide and rape also impacts various aspects of biological regulation, including patterns of DNA methylation, remains unknown. The purpose of this study was to evaluate whether prenatal exposure to genocide-related trauma, including conception through rape, is associated with accelerated epigenetic aging, a molecular indicator of biological aging.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that prenatal exposure to genocide-related trauma is associated with accelerated epigenetic aging. This research is relevant as it explores the impact of early-life trauma on biological aging, which could provide insights into the root causes of aging and its implications for longevity.

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