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RESEARCH PAPER / 2025-08-10

Aging and anti-aging strategies: A review of past and future therapeutics.

Yuqing Wei, Baichen Xiong, Zuoaoyun Song, Sheng Zhong, Na Zheng, Ao Zhang, Yao Chen, Haopeng Sun

School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China. · pubmed

Abstract

Aging is a progressive degenerative state characterized by a gradual loss of physiological fitness, resulting in deteriorated functions and susceptibility to age-related diseases. With the progress of research on aging and age-related mechanisms, identifying effective anti-aging drugs has become a key focus. In this review, we summarize aging and its related signaling pathways and targets, mainly including clearance of senescent cells, NAD

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper reviews various anti-aging strategies and signaling pathways related to aging. The focus on identifying effective anti-aging drugs and mechanisms aligns with addressing the root causes of aging, making it relevant to longevity research.

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