Associations of Midlife Leukocyte Telomere Length With Measures of Left Atrial Function in Community-Dwelling Older Adults: The ARIC Study.

Romil R Parikh, Nathan Pankratz, John A Lane, Dan E Arking, Anne Eaton, Lin Yee Chen, Pamela L Lutsey, Weihong Tang

Division of Epidemiology and Community Health University of Minnesota School of Public Health Minneapolis MN USA.Division of Epidemiology and Community Health University of Minnesota School of Public Health Minneapolis MN USA. · pubmed

Paper

Abstract

It is unknown whether atrial myopathy, ascertained by poor left atrial (LA) function, is associated with biological aging independent of chronological age. Such an association would indicate that atrial myopathy may be preventable by intervening on modifiable risk factors that accelerate aging. Therefore, we evaluated associations of midlife leukocyte telomere length (LTL, a measure of biological aging) with measures of LA function (a surrogate for LA myopathy).

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Research summary

The paper claims that midlife leukocyte telomere length is associated with measures of left atrial function, suggesting a link between biological aging and atrial myopathy. This research is relevant as it explores biological aging markers and their potential implications for preventing age-related cardiac conditions.

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