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RESEARCH PAPER / 2025-08-06

Redox-regulated signalling of adaptations to contractile activity in skeletal muscle: Implications for age-related muscle weakness.

Malcolm J Jackson

Department of Musculoskeletal and Ageing Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.Department of Musculoskeletal and Ageing Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK. · pubmed

Abstract

Skeletal muscle adaptation to contractile activity is modulated by redox signalling, primarily through reactive oxygen species (ROS) such as hydrogen peroxide (H

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that redox signalling through reactive oxygen species modulates skeletal muscle adaptations to contractile activity. This research is relevant as it explores mechanisms that could address age-related muscle weakness, which is a significant aspect of aging and longevity.

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