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RESEARCH PAPER / 2025-08-04

Ganoderma lucidum sporoderm-broken spore powder alleviates kidney aging by modulating gut microbiota.

Xiaojing Liu, Jiamin Zhao, Jia Liu, Wei Deng, Luwen Yan, Yan Huang, Liao Zhang, Zhihong Liu, Ming Cui, Huiwen Xiao, Xingzhong Liu

State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, 94 Weijin Road, Tianjin, 300071, China.State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, 94 Weijin Road, Tianjin, 300071, China. · pubmed

Abstract

Ganoderma lucidum (G. lucidum), a revered medicinal mushroom in traditional Chinese medicine (TCM), has been historically documented for its anti-aging properties and nephroprotective effects. Nevertheless, its mechanism of action through gut microbiota modulation to attenuate renal and systemic aging remains incompletely understood.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Ganoderma lucidum sporoderm-broken spore powder modulates gut microbiota to alleviate kidney aging. The paper is relevant as it explores a potential mechanism for addressing aging through gut microbiota, which may influence systemic aging processes.

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