Cumulative psychosocial factors and epigenetic age acceleration in the Hispanic Community Health Study/Study of Latinos.

Sarina Abrishamcar, Jasmine K Aqua, Christian Dye, Rebecca Jones-Antwi, Yinxian Chen, Linda C Gallo, Maria M Llabre, Krista M Perreira, Martha L Daviglus, Maria Argos, Bharat Thyagarajan, Anke Hüls, Andrea Baccarelli, Jianwen Cai, Carmen R Isasi, Robert C Kaplan, Karen N Conneely, Shakira F Suglia

Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA. · pubmed

Paper

Abstract

Hispanics/Latinos in the United States experience disproportionately high psychosocial factors compared to non-Hispanic/Latino Whites. Psychosocial factors may accelerate biological aging, measured by epigenetic age acceleration (EAA), a DNA methylation biomarker predictive of morbidity and mortality.

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Research summary

Psychosocial factors contribute to epigenetic age acceleration in the Hispanic community. The study addresses the relationship between psychosocial stressors and biological aging, which is pertinent to understanding the root causes of aging and potential interventions.

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