Age- and sex-associated differences in immune cell populations.

Reza Gheitasi, Sabine Baumgart, Daniela Roell, Norman Rose, Carsten Watzl, Diana Dudziak, Nico Andreas, Oliwia Makarewicz, Sebastian Drube, Clara Schnizer, Thomas Kamradt, Sebastian Weis, Mathias W Pletz

Institute for Infectious Diseases and Infection Control, Jena University Hospital, Friedrich-Schiller-University Jena, 07747 Jena, Germany.Institute for Infectious Diseases and Infection Control, Jena University Hospital, Friedrich-Schiller-University Jena, 07747 Jena, Germany. · pubmed

Paper

Abstract

Aging is associated with the risk of increased infection severity and altered immune responses. In this study we investigated age- and sex-specific differences in immune cell composition in a subset of the population-based CoNAN study using a cross-sectional analysis. We identified a significant age × sex interaction in memory B cells and observed age-related declines in naive lymphocytes and an increase in CD8

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Research summary

The paper identifies significant age- and sex-associated differences in immune cell populations. This research contributes to understanding how aging affects immune function, which is crucial for addressing age-related diseases and longevity.

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