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RESEARCH PAPER / 2025-07-31

Association between coffee intake and serum α-Klotho levels in adults: a population-based study.

Xiaoyan Tang, Hu Tuo, Cui Cao, Zhao Yang, Shaohua Zhang, Rui Du

Department of Cardiology, General Hospital of Central Theater Command, No.627, Wuluo Road, Wuhan, 430070, China. · pubmed

Abstract

Coffee is widely consumed in the US, linked to various health benefits, including reduced adiposity. α-Klotho is a circulating protein linked to the aging processes, associated with greater longevity, and confers protective effects against cardiovascular disease, chronic kidney disease, and neurodegenerative disorders. This study investigates the association between coffee (total, caffeinated, and decaffeinated) intake and serum α-Klotho (SαKl) levels.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that there is an association between coffee intake and serum α-Klotho levels in adults. The study is relevant as it explores a potential link between a common dietary factor (coffee) and a biomarker (α-Klotho) associated with aging and longevity.

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