Sleep disorders and aging: Mendelian randomization analysis of epigenetic and frailty markers.

Zheng Zhang, Hao Ren, Yongjia Cheng, Haitang Qiu, Qinghua Luo, Yuan Zhao, Jiangyou Yu, Chenggang Jiang

Department of Sleep and Psychology, Chongqing Health Center for Women and Children, Chongqing 401147, China; Department of Sleep and Psychology, Women and Children's Hospital of Chongqing Medical University, 401147, China; Chongqing Research Center for Prevention & Control of Maternal and Child Diseases and Public Health, 401147, China.Department of Sleep and Psychology, Chongqing Health Center for Women and Children, Chongqing 401147, China; Department of Sleep and Psychology, Women and Children's Hospital of Chongqing Medical University, 401147, China; Chongqing Research Center for Prevention & Control of Maternal and Child Diseases and Public Health, 401147, China. · pubmed

Paper

Abstract

Sleep disorders-including daytime sleepiness (DS), insomnia, and sleep apnea (SA)-have been linked to aging-related phenotypes, but their causal roles remain unclear. This study aimed to examine the potential causal effects of these sleep traits on biological aging using a Mendelian randomization (MR) approach.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims to investigate the causal effects of sleep disorders on biological aging using a Mendelian randomization approach. This research is relevant as it explores the relationship between sleep disorders and biological aging, potentially addressing underlying mechanisms that contribute to aging processes.

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