Healing hearts and mending minds (FitBrain): a home-based aerobic exercise intervention to improve cognitive outcomes in older persons living with HIV.

Drenna Waldrop, Raphiel Murden, Crista Irwin, Jordan Pelkmans, Rebecca Gary

Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA. · pubmed

Paper

Abstract

Advances in antiviral treatment for HIV have led to greater longevity but there is continued risk for developing cardiovascular disease and cognitive impairment, particularly among older persons with HIV (PWH). The benefits of aerobic exercise for reducing cardiovascular disease are well established and have been shown to improve cognitive function in older adults but has had limited testing in older PWH and are inconclusive. This study aimed to test the efficacy of a home-based moderate intensity aerobic exercise intervention (Let's Move) to an attention control stretching and flexibility group (Let's Flex) over a one-year period among PWH with mild cognitive impairment and a minimum of 2 cardiovascular disease risk factors. Clinically stable (

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Research summary

The paper claims that a home-based aerobic exercise intervention can improve cognitive outcomes in older persons living with HIV. This research addresses cognitive impairment and cardiovascular disease risk in older adults, which are significant concerns in the context of longevity and aging.

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