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RESEARCH PAPER / 2025-07-30

The impact of ER

Priyanka Mallick, Sebabrata Maity, Rupsha Mondal, Trina Roy, Puyam Milan Meitei, Shashank Saxena, Bhavani Shankar Sahu, Oishee Chakrabarti, Saikat Chakrabarti

Structural Biology and Bioinformatics Division, CSIR-Indian Institute of Chemical Biology, IICB TRUE Campus, CN-6, Sector 5, Kolkata, 700091, India. · pubmed

Abstract

ER and mitochondrial stress are often interconnected and considered major contributors to aging as well as neurodegeneration. Coordinated induction of ER

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the interconnectedness of endoplasmic reticulum (ER) and mitochondrial stress as contributors to aging and neurodegeneration. This research addresses mechanisms that could be linked to the root causes of aging, rather than merely treating symptoms of age-related diseases.

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